Irvingia Gabonensis

Irvingia Gabonensis is a tree in the family Irvingiaceae, and is sometimes known as wild mango, African mango, or bush mango. The seeds from the fruit of this tree have been investigated as a factor in weight loss and blood lipid panel improvement.

In a 2005 study, the efficacy of Irvingia gabonensis (IG) seeds in the management of obesity was evaluated. In a double blind randomised study involving 40 subjects, twenty-eight subjects received IG while 12 were on placebo and the same schedule.

During the one-month study period all subjects were on a normal diet evaluated every week by a dietetic record book. At the end, the mean body weight of the IG group was decreased by 5.26 ± 2.37% (p < 0.0001) and that of the placebo group by 1.32 ± 0.41% (p < 0.02).

The difference observed between the IG and the placebo groups was significant (p < 0.01). The obese patients under IG treatment also had a significant decrease of total cholesterol, LDL-cholesterol, triglycerides, and an increase of HDL-cholesterol.

On the other hand, the placebo group did not manifest any changes in blood lipid components. IG seed may find application in weight loss.

Other studies have also shown a beneficial effect on weight loss in combination with another plant extract, Cissus quadrangularis. IG is also used medicinally in most parts of tropical Africa for the treatment of a number of ailments. In West Africa the Mende tribe of Sierra Leone uses the stem bark to relieve pain. One study confirmed this pain relieving property. (Journal of Ethnopharmacology Volume 45, Issue 2, February 1995, Pages 125-129)

Here’s another more technical study on this substance.

Done with Irvingia Gabonensis, back to Research on Obesity