Irvingia Gabonensis is a tree in the family Irvingiaceae and is sometimes known as wild mango, African mango, or bush mango. The seeds from the fruit of this tree have been investigated as a factor in weight loss and blood lipid panel improvement.
In a 2005 study, the efficacy of Irvingia gabonensis (IG) seeds in the management of obesity was evaluated. In a double blind randomised study involving 40 subjects, twenty-eight subjects received IG while 12 were on placebo and the same schedule.
During the one-month study period all subjects were on a normal diet evaluated every week by a dietetic record book. At the end, the mean body weight of the IG group was decreased by 5.26 ± 2.37% (p < 0.0001) and that of the placebo group by 1.32 ± 0.41% (p < 0.02).
The difference observed between the IG and the placebo groups was significant (p < 0.01). The obese patients under IG treatment also had a significant decrease of total cholesterol, LDL-cholesterol, triglycerides, and an increase of HDL-cholesterol.
On the other hand, the placebo group did not manifest any changes in blood lipid components. IG seed may find application in weight loss.
Other studies have also shown a beneficial effect on weight loss in combination with another plant extract, Cissus quadrangularis. IG is also used medicinally in most parts of tropical Africa for the treatment of a number of ailments. In West Africa, the Mende tribe of Sierra Leone uses the stem bark to relieve pain. One study confirmed this pain-relieving property. (Journal of Ethnopharmacology Volume 45, Issue 2, February 1995, Pages 125-129)